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教授
孙联文
职务职称:教授 博士生导师
办公地点:逸夫楼405
联系电话:82339349
E:mail :sunlw@buaa.edu.cn
 

孙联文  

北京航空航天大学  金沙总站6165app  教授、博士生导师、工会主席

Lianwen Sun, Ph.D. & Professor

Business Address: Room 405, Yifu Building

School of Biological Science and Medical Engineering, Beihang University, Beijing

 

主要教育、科研简历:

1991-1996      天津医科大学医疗系,临床医学                                                          医学学士学位

1996-2001      中国协和医科大学,皮肤与性病学                                                      医学博士学位

2001-2004      北京航空航天大学,生物工程系                                                          讲师

2004-2008      北京航空航天大学,生物工程系                                                      副教授、副主任

2005-2006      德国柏林自由大学&洪堡大学Charité医学院                                     访问学者       

2008-2010      北京航空航天大学,金沙总站6165app                                      副教授、副院长

2010                Charité医科大学,柏林空天医学中心                                                 访问学者

2010-2012      北京航空航天大学,金沙总站6165app                                         教授、副院长

2015                德州大学圣安东尼奥分校                                                                       访问学者

2016                Charité医科大学,柏林空天医学中心                                                 高级访问学者

2017                英国伦敦大学学院                                                                                    高级访问学者

2012-现在       北京航空航天大学,金沙总站6165app                                        教授、工会主席

Education:

1991-1996      B.M.                                                                    School of Astronautics, Beihang University

1996-2001      Ph. D. & M.D.                                                     Dermatology, Peking Union Medical College

Professional Experience:

2001-2004      Lecturer                                                          Bioengineering Department, Beihang University

2004-2008      Associate Professor & Vice Director              Bioengineering Department, Beihang University

2005-2006      Visiting Scholar                                                  Charité College of Medicine, Humboldt University & Free University of Berlin, Germany

2008-2010      Associate Professor & Vice Dean                    School of Biological Science and Medical Engineering,  Beihang University

2010        Visiting Scholar                                                  Berlin space medical center, Charité Medical University

2010-2012      Professor & Vice Dean                                      School of Biological Science and Medical Engineering,Beihang University

2015        Visiting Scholar                                                  The University of Texas at San Antonio

2016        Senior Visiting Scholar                                      Berlin space medical center, Charité Medical University

2016        Senior Visiting Scholar                                      University College London

2012-present  Professor & Trade union chairman                  School of Biological Science and Medical Engineering,Beihang University

 

主要研究方向:

1.       航空航天生物医学工程

2.       空间生命科学

3.       生物力学与力生物学

Research Interests

1.       Aviation and Space Biomedical Engineering

2.       Space Life Science

3.       Biomechanics and Mechanobiology

 

主要社会兼职:

1. 中国空间科学学会空间生命专业委员会副主任委员

2. 中国空间科学学会常务理事

3. 全国空间科学及应用标准化技术委员会(生命交叉科学)标准化工作组成员

 

近期主要论著(Recent Publications Selected:

[1]       Dong Ding, Xiao Yang, Huiqin Luan, Xintong Wu, Lianwen Sun*, Yubo Fan*. The microgravity induces the ciliary shortening and an increased ratio of anterograde/retrograde intraflagellar transport of osteocytes. Biochemical and Biophysical Research Communications, 2020, 530: 167-172.

[2]       Dong Ding, Xiao Yang, Huiqin Luan, Xintong Wu, Cai He, Lianwen Sun*, Yubo Fan*. Pharmacological Regulation of Primary Cilium Formation Affects the Mechanosensitivity of Osteocytes. Calcified Tissue International, 2020: 1-11.

[3]       Wen Xiao, Qixiang Wang, Feng Pan, Runyu Cao, Xintong Wu, Lianwen Sun*. Adaptive frequency filtering based on convolutional neural networks in off-axis digital holographic microscopy. Biomedical Optical Express. 2019, 10.

[4]       Xintong Wu, Wen Xiao, Runyu Cao, Xiao Yang, Feng Pan, Lianwen Sun*, Yubo Fan*. Spontaneous cellular vibratory motions of osteocytes are regulated by ATP and spectrin network. Bone, 128 (2019), 112056.

[5]       Shouhui Wang, Wenting Li, Xiao Yang, Yunfei Huang, Lianwen Sun*, Yubo Fan. Musculoskeletal alterations of hindlimb during simulated microgravity and reloading in rats: compared by gender. Microgravity Science and Technology. 2019, 31(4): 347-355. 

[6]       Dong Ding, Xiao Yang, Huiqin Luan, Xintong Wu, Lianwen Sun*, Yubo Fan*. The microgravity induces the ciliary shortening and an increased ratio of anterograde/retrograde intraflagellar transport of osteocytes. Biochemical and Biophysical Research Communications, 2020, 530: 167-172.

[7]       Shouhui Wang, Xiao Yang, Min Wang, Yunfei Huang, Dieter Blottner, Lianwen Sun*, Yubo Fan*. The role of body fluid shifts on hindlimb bone loss in tail suspended rats using a novel body fluid alteration device. Acta Astronautica. 2019, 159:1-7.

[8]       Yunfei Huang, Huiqin Luan, Lianwen Sun*, Shouhui Wang, Yubo Fan*. Increased Blood Flow by Unilateral Intermittent Compression on Hindlimbs May Prevent Bone Loss. Microgravity Science and Technology, 2018, 30: 987-993.

[9]       Lianwen Sun, Shuang Li, Xiao Yang, Fang Pu, Hongyu Qi*, Yubo Fan*. Contribution of bone micromechanical behavior beyond lamellar length scale to the macroscopic bone quality of hind limb unloading rats. Acta Astronautica. 2018, 152: 468–473.

[10]   Yunfei Huang, Yubo Fan, Michele Salanova, Xiao Yang, Lianwen Sun*, Dieter Blottner. Effects of Plantar Vibration on Bone and Deep Fascia in a Rat Hindlimb Unloading Model of Disuse. Frontiers in Physiology, 2018, 9: 616.

[11]   Xiao Yang, Lianwen Sun*, Chengfei Du, Xintong Wu, Yubo Fan*. Finite element analysis of osteocytes mechanosensitivity under simulated microgravity, Microgravity Science and Technology, 2018, 30: 469-481.

[12]   Runyu Cao, Wen Xiao, Xintong Wu, Lianwen Sun*, Feng Pan*. Quantitative observations on cytoskeleton changes of osteocytes at different cell parts using digital holographic microscopy. Biomedical Optics Express 2018, 9(1): 72-85.

[13]   Yunfei Huang, Huiqin Luan, Lianwen Sun*, Jingfang Bi, Ying Wang, Yubo Fan*. Local vibration enhanced the efficacy of passive exercise on mitigating bone loss in hindlimb unloading rats. Acta Astronautica, 2017, 137: 373-381.

[14]   Xintong Wu, Lianwen Sun*, Xiao Yang, Dong Ding, Dong Han, Yubo Fan*. The potential role of spectrin network in the mechanotransduction of MLO-Y4 osteocytes. Sci Rep. 2017, 7: 40940.

[15]   Wenting Li, Yunfei Huang, Lianwen Sun*, Huiqin Luan, Baozhang Zhu, Yubo Fan*. Would interstitial fluid flow be responsible for skeletal maintenance in tail-suspended rats? [J]. Microgravity Science and Technology, 2017(29): 107-114.

[16]   Xiao Yang, Ahmed JenanMostafa, Mark Appleford, Lianwen Sun*, Xiaodu Wang*. Bone formation is affected by matrix advanced glycation end products (AGEs) in vivo. Calcified tissue international 2016, 99(4): 373-383.

[17]   Xintong Wu, Lianwen Sun*, Hongyu Qi, Hao Shi, Yubo Fan*. The bio-response of osteocytes and its regulation on osteoblasts under vibration. Cell Biology International, 2016, 40(4): 397-406.

[18]   Huiqin Luan, Lianwen Sun*, Yunfei Huang, Xintong Wu, Haijun Niu, Hong Liu, Yubo Fan*. Use of micro-computed tomography to evaluate the effects of exercise on preventing the degeneration of articular cartilage In tail-suspended rats. Life Sciences in Space Research, 2015, 6, 15-20.

[19]   Xiao Yang, Chintan Gandhi, Md. MizanurRahman, Mark Appleford, Lianwen Sun*,Xiaodu Wang*. Age-related effects of advanced glycation end products (ages) in bone matrix on osteoclastic resorption. Calcified tissue international, 2015, 97:592-601.

[20]   Xiao Yang, Lianwen Sun*, Xintong Wu, Meng Liang, Yubo Fan*. Impact of shear stress and simulated microgravity on osteocytes using a new rotation cell culture device.ActaAstronautica, 2015, 116, 286-298.

[21]   Xiao Yang, Lianwen Sun*, Meng Liang, Xiaonan Wang, Yubo Fan*. The response of wnt/β-catenin signaling pathway in osteocytes under simulated microgravity. Microgravity Science and Technology. 2015, 27:473-483.

[22]   Lianwen Sun*, Yunfei Huang, Ying Wang , Hui-Qin Luan, Yubo Fan*,Comparison of bone histomorphometry and µCT for evaluating bone quality in tail-suspended rats. Life Sciences in Space Research, 2014, 3,18-23.

[23]   Huiqin Luan, Lianwen Sun*, Yunfei Huang, Ying Wang, Colin J. McClean, Yubo Fan*. The application of micro-CT in monitoring bone alterations in tail-suspended rats in vivo. Advances in Space Research, 2014, 53(11): 1567-1573.

[24]   Lianwen Sun*, Huiqin Luan, Yunfei Huang, Ying Wang, Yubo Fan. Effects of local vibration on bone loss in tail-suspended rats. Int J Sports Med, 2014,35(7): 615-624.

[25]   Lianwen Sun, Blottner Dieter, Huiqing Luan, Salanova Michele, Wang Chao, Haijun Niu, Felsenberg Dieter, Yubo Fan. Bone and muscle structure and quality preserved by active versus passive muscle exercise on a new stepper device in 21 days tail-suspended rats.J Musculoskelet Neuronal Interact. 2013, 13(2):166-77.

[26]   Xiao Yang, Lianwen Sun*, Xintong Wu, Xiaonan Wang, Yubo Fan. Effect of simulated microgravity on osteocytes responding to fluid shear stress[J]. Acta Astronautica, 2013, 84(MAR.-APR.):237-243.

[27]   Lianwen Sun, Chao Wang, Fang Pu, Deyu Li, Haijun Niu, Yubo Fan*. Comparative Study on Measured Variables and Sensitivity to Bone Microstructural Changes Induced by Weightlessness Between In Vivo and Ex Vivo Micro-CT Scan. Calcified Tissue International(Calcified Tissue Int),2011, 88(1):48-53.

[28]   Beller Gisela, Belavý Daniel, Lianwen Sun, Armbrecht Gabi, Alexandre Christian, Felsenberg Dieter. WISE-2005: bed-rest induced changes in bone mineral density in women during 60 days simulated microgravity. Bone, 2011, 49(4):858-66.

[29]   Xiao Yang, Lianwen Sun, Xiaonan Wang, Yubo Fan*. Effects of simulated microgravity on the mechanosensibility of osteocytes due to fluid shear stress. Bone, 2010, Vol 47(S3), S436-S437.

[30]   Lianwen Sun, Chao Wang, Tian Xie, Fang Pu, Yao Sun, Yubo Fan*. Body-weight distribution on forelimbs in rat tail-suspension model[J]. Aviakosmicheskaya i Ekologicheskaia MeditsinaAerospace and environmental medicine,  

2010, 44(1):37-39.

 

发明专利:

1.       一种模拟失重状态下大鼠体液分布的调节装置. 孙联文,王守辉,王敏,樊瑜波. ZL201610603340.2

2.       一种模拟失重尾吊大鼠主/被动运动训练装置的定位装置. 孙联文,谢添,樊瑜波,贡向辉. ZL200910249644.3

3.       一种模拟失重尾吊大鼠主/被动运动训练装置. 孙联文,谢添,樊瑜波,贡向辉. ZL200810114305.X

4.       一种单轴旋转在线剪切体外细胞培养装置. 樊瑜波,杨肖孙联文,贡向辉. ZL201110060145.7

5.       一种中空传动轴内嵌液路旋转接头与中空传动轴连接件. 杨肖,李双,何源,孙联文. ZL201911079044.7